Following a close second is Sulfur, usually supplemented in the form of MSM, whose main action in addition to helping restore cartilage formation is the lowering of copper! So again, it is the high copper levels which created a need for sulfur to help reverse joint degeneration. Originally, glucosamine sulfate had been the non-drug treatment of choice for joint problems, however its blood sugar raising potential has considerably reduced its popularity in individuals with blood sugar disturbances, so MSM has become the preferred choice instead... Full Text